Vestibulodynia, formally referred to as Vulvar Vestibulitis is pain in the vestibule (vaginal opening) of the vulva that may be caused by infection, various skin conditions, inflammation, certain diseases or neurologic or musculoskeletal disorders. Patients with Vestibulodynia often experience pain during intercourse, when sitting and/or when wearing tight clothing. A sensitivity to skin creams and soaps is also reported by some Vestibulodynia patients. Pain from this condition may change at different points throughout the monthly menstrual cycle.